1. 2024
  2. Производные имидазолидин-2,4-диона и имидазолидин-2,4,5-триона на основе смоляных кислот, проявляющие антиинвазивную активность в отношении клеток глиобластомы линий T98G и SNB19

    Чересиз, С. В., Ковалева, К. С., Яровая, О. И., Салахутдинов, Н. Ф. & Покровский, А. Г., 17 Jun 2024, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2821104, 8 Dec 2023, Priority date 8 Dec 2023, Priority No. 2023132332

    Research output: PatentPatent for invention

  3. 2023
  4. Development of an LC-MS/MS-based method for quantification and pharmacokinetics study on SCID mice of a dehydroabietylamine-adamantylamine conjugate, a promising inhibitor of the DNA repair enzyme

    Okhina, A. A., Rogachev, A. D., Kovaleva, K. S., Yarovaya, O. I., Khotskina, A. S., Zavyalov, E. L., Vatsadze, S. Z., Pokrovsky, A. G. & Salakhutdinov, N. F., 20 Sept 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 234, 115507.

    Research output: Contribution to journalArticlepeer-review

  5. Synthesis of N-heterocyclic amides based on (+)-camphoric acid and study of their antiviral activity and pharmacokinetics

    Yarovaya, O. I., Baranova, D. V., Sokolova, A. S., Nemolochnova, A. G., Sal'nikova, O. P., Fat'anova, A. V., Rogachev, A. D., Volobueva, A. S., Zarubaev, V. V., Pokrovsky, A. G. & Salakhutdinov, N. F., Mar 2023, In: Russian Chemical Bulletin. 72, 3, p. 807-818 12 p.

    Research output: Contribution to journalArticlepeer-review

  6. Structure-Based Design, Synthesis, and Biological Evaluation of the Cage-Amide Derived Orthopox Virus Replication Inhibitors

    Mozhaitsev, E. S., Suslov, E. V., Rastrepaeva, D. A., Yarovaya, O. I., Borisevich, S. S., Khamitov, E. M., Kolybalov, D. S., Arkhipov, S. G., Bormotov, N. I., Shishkina, L. N., Serova, O. A., Brunilin, R. V., Vernigora, A. A., Nawrozkij, M. B., Agafonov, A. P., Maksyutov, R. A., Volcho, K. P. & Salakhutdinov, N. F., 1 Jan 2023, In: Viruses. 15, 1, 29.

    Research output: Contribution to journalArticlepeer-review

  7. Synthesis of conjugates of (aR,7S)-colchicine with monoterpenoids and investigation of their biological activity

    Shchegravina, E. S., Usova, S. D., Baev, D. S., Mozhaitsev, E. S., Shcherbakov, D. N., Belenkaya, S. V., Volosnikova, E. A., Chirkova, V. Y., Sharlaeva, E. A., Svirshchevskaya, E. V., Fonareva, I. P., Sitdikova, A. R., Salakhutdinov, N. F., Yarovaya, O. I. & Fedorov, A. Y., 1 Jan 2023, In: Russian Chemical Bulletin. 72, 1, p. 248-262 15 p.

    Research output: Contribution to journalArticlepeer-review

  8. Synthesis of non-symmetric N-benzylbispidinol amides and study of their inhibitory activity against the main protease of the SARS-CoV-2 virus

    Dalinger, A. I., Baev, D. S., Yarovaya, O. I., Chirkova, V. Y., Sharlaeva, E. A., Belenkaya, S. V., Shcherbakov, D. N., Salakhutdinov, N. F. & Vatsadze, S. Z., 1 Jan 2023, In: Russian Chemical Bulletin. 72, 1, p. 239-247 9 p.

    Research output: Contribution to journalArticlepeer-review

  9. Corrigendum: The main protease 3CLpro of the SARS-CoV-2 virus: how to turn an enemy into a helper

    Belenkaya, S. V., Merkuleva, I. A., Yarovaya, O. I., Chirkova, V. Y., Sharlaeva, E. A., Shanshin, D. V., Volosnikova, E. A., Vatsadze, S. Z., Khvostov, M. V., Salakhutdinov, N. F. & Shcherbakov, D., 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1294266.

    Research output: Contribution to journalArticlepeer-review

  10. The main protease 3CLpro of the SARS-CoV-2 virus: how to turn an enemy into a helper

    Belenkaya, S. V., Merkuleva, I. A., Yarovaya, O. I., Chirkova, V. Y., Sharlaeva, E. A., Shanshin, D. V., Volosnikova, E. A., Vatsadze, S. Z., Khvostov, M. V., Salakhutdinov, N. F. & Shcherbakov, D. N., 2023, In: Frontiers in Bioengineering and Biotechnology. 11, 1187761.

    Research output: Contribution to journalArticlepeer-review

  11. 2022
  12. Nitrogen-Containing Heterocyclic Compounds Obtained from Monoterpenes or Their Derivatives: Synthesis and Properties

    Chernyshov, V. V., Popadyuk, I. I., Yarovaya, O. I. & Salakhutdinov, N. F., Oct 2022, In: Topics in current chemistry (Cham). 380, 5, p. 42 1 p., 42.

    Research output: Contribution to journalReview articlepeer-review

  13. Synthesis and Antiviral Properties of Camphor-Derived Iminothiazolidine-4-Ones and 2,3-Dihydrothiazoles

    Oreshko, V. V., Kovaleva, K. S., Mordvinova, E. D., Yarovaya, O. I., Gatilov, Y. V., Shcherbakov, D. N., Bormotov, N. I., Serova, O. A., Shishkina, L. N. & Salakhutdinov, N. F., Aug 2022, In: Molecules. 27, 15, 4761.

    Research output: Contribution to journalArticlepeer-review

  14. Design, Synthesis, and Biological Evaluation of (+)-Camphor- and (−)-Fenchone-Based Derivatives as Potent Orthopoxvirus Inhibitors

    Sokolova, A. S., Kovaleva, K. S., Kuranov, S. O., Bormotov, N. I., Borisevich, S. S., Zhukovets, A. A., Yarovaya, O. I., Serova, O. A., Nawrozkij, M. B., Vernigora, A. A., Davidenko, A. V., Khamitov, E. M., Peshkov, R. Y., Shishkina, L. N., Maksuytov, R. A. & Salakhutdinov, N. F., 20 Jun 2022, In: ChemMedChem. 17, 12, p. e202100771 26 p., e202100771.

    Research output: Contribution to journalArticlepeer-review

  15. Inhibition of the DNA repair enzyme TDP1 by the resin acid derivatives as a new way to increase the efficiency of glioblastoma chemotherapy

    Kovaleva, K., Oleshko, O., Yarovaya, O., Cheresiz, S., Zakharenko, A., Ponomarev, K., Lavrik, O., Pokrovsky, A. & Salakhutdinov, N., 4 Feb 2022, Actual Problems of Organic Chemistry and Biotechnology, OCBT 2020: Proceedings of the International Scientific Conference. Bakulev, V., Kovaleva, E., Glukhareva, T., Beryozkina, T., Schafran, Y., Lyubyakina, P. & Koptyaeva, O. (eds.). American Institute of Physics Inc., 020036. (AIP Conference Proceedings; vol. 2390).

    Research output: Chapter in Book/Report/Conference proceedingConference contributionResearchpeer-review

  16. Design and Evaluation of Bispidine-Based SARS-CoV-2 Main Protease Inhibitors

    Shcherbakov, D., Baev, D., Kalinin, M., Dalinger, A., Chirkova, V., Belenkaya, S., Khvostov, A., Krut'Ko, D., Medved'Ko, A., Volosnikova, E., Sharlaeva, E., Shanshin, D., Tolstikova, T., Yarovaya, O., Maksyutov, R., Salakhutdinov, N. & Vatsadze, S., 13 Jan 2022, In: ACS Medicinal Chemistry Letters. 13, 1, p. 140-147 8 p.

    Research output: Contribution to journalArticlepeer-review

  17. Synthesis and In Vitro Study of Antiviral Activity of Glycyrrhizin Nicotinate Derivatives against HIV-1 Pseudoviruses and SARS-CoV-2 Viruses

    Fomenko, V. V., Rudometova, N. B., Yarovaya, O. I., Rogachev, A. D., Fando, A. A., Zaykovskaya, A. V., Komarova, N. I., Shcherbakov, D. N., Pyankov, O. V., Pokrovsky, A. G., Karpenko, L. I., Maksyutov, R. A. & Salakhutdinov, N. F., 1 Jan 2022, In: Molecules. 27, 1, 295.

    Research output: Contribution to journalArticlepeer-review

  18. 2021
  19. Dehydroabietylamine-based thiazolidin-4-ones and 2-thioxoimidazolidin-4-ones as novel tyrosyl-DNA phosphodiesterase 1 inhibitors

    Kovaleva, K., Mamontova, E., Yarovaya, O., Zakharova, O., Zakharenko, A., Lavrik, O. & Salakhutdinov, N., Nov 2021, In: Molecular Diversity. 25, 4, p. 2389-2397 9 p.

    Research output: Contribution to journalArticlepeer-review

  20. Stability study of the antiviral agent camphecene in dried blood spots at different temperatures

    Okhina, A. A., Rogachev, A. D., Yarovaya, O. I., Pokrovsky, A. G. & Salakhutdinov, N. F., Oct 2021, In: Drug Testing and Analysis. 13, 10, p. 1797-1802 6 p.

    Research output: Contribution to journalLetterpeer-review

  21. Biostability study, quantitation method and preliminary pharmacokinetics of a new antifilovirus agent based on borneol and 3-(piperidin-1-yl)propanoic acid

    Rogachev, A. D., Putilova, V. P., Zaykovskaya, A. V., Yarovaya, O. I., Sokolova, A. S., Fomenko, V. V., Pyankov, O. V., Maksyutov, R. A., Pokrovsky, A. G. & Salakhutdinov, N. F., 30 May 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 199, 114062.

    Research output: Contribution to journalArticlepeer-review

  22. Design, synthesis, and molecular docking study of new tyrosyl-dna phosphodiesterase 1 (Tdp1) inhibitors combining resin acids and adamantane moieties

    Kovaleva, K., Yarovaya, O., Ponomarev, K., Cheresiz, S., Azimirad, A., Chernyshova, I., Zakharenko, A., Konev, V., Khlebnikova, T., Mozhaytsev, E., Suslov, E., Nilov, D., Švedas, V., Pokrovsky, A., Lavrik, O. & Salakhutdinov, N., 1 May 2021, In: Pharmaceuticals. 14, 5, 422.

    Research output: Contribution to journalArticlepeer-review

  23. Unexpected Ring Opening During the Imination of Camphor-Type Bicyclic Ketones

    Chernyshov, V. V., Yarovaya, O. I., Vatsadze, S. Z., Borisevich, S. S., Trukhan, S. N., Gatilov, Y. V., Peshkov, R. Y., Eltsov, I. V., Martyanov, O. N. & Salakhutdinov, N. F., 22 Jan 2021, In: European Journal of Organic Chemistry. 2021, 3, p. 452-463 12 p.

    Research output: Contribution to journalArticlepeer-review

  24. 2020
  25. Monoterpenoid-based inhibitors of filoviruses targeting the glycoprotein-mediated entry process

    Sokolova, A. S., Yarovaya, O. I., Zybkina, A. V., Mordvinova, E. D., Shcherbakova, N. S., Zaykovskaya, A. V., Baev, D. S., Tolstikova, T. G., Shcherbakov, D. N., Pyankov, O. V., Maksyutov, R. A. & Salakhutdinov, N. F., 1 Dec 2020, In: European Journal of Medicinal Chemistry. 207, 17 p., 112726.

    Research output: Contribution to journalArticlepeer-review

  26. New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections

    Suslov, E. V., Mozhaytsev, E. S., Korchagina, D. V., Bormotov, N. I., Yarovaya, O. I., Volcho, K. P., Serova, O. A., Agafonov, A. P., Maksyutov, R. A., Shishkina, L. N. & Salakhutdinov, N. F., Oct 2020, In: RSC Medicinal Chemistry. 11, 10, p. 1185-1195 11 p.

    Research output: Contribution to journalArticlepeer-review

  27. Synthesis of cyclic D-(+)-camphoric acid imides and study of their antiviral activity

    Chernyshov, V. V., Yarovaya, O. I., Peshkov, R. Y. & Salakhutdinov, N. F., 1 Jun 2020, In: Chemistry of Heterocyclic Compounds. 56, 6, p. 763-768 6 p.

    Research output: Contribution to journalArticlepeer-review

  28. Single-stage synthesis of heterocyclic alkaloid-like compounds from (+)-camphoric acid and their antiviral activity

    Chernyshov, V. V., Yarovaya, O. I., Fadeev, D. S., Gatilov, Y. V., Esaulkova, Y. L., Muryleva, A. S., Sinegubova, K. O., Zarubaev, V. V. & Salakhutdinov, N. F., 1 Feb 2020, In: Molecular Diversity. 24, 1, p. 61-67 7 p.

    Research output: Contribution to journalArticlepeer-review

  29. 2019
  30. Synthesis and structure-activity relationships of novel camphecene analogues as anti-influenza agents

    Yarovaya, O. I., Sokolova, A. S., Mainagashev, I. Y., Volobueva, A. S., Lantseva, K., Borisevich, S. S., Shtro, A. A., Zarubaev, V. V. & Salakhutdinov, N. F., 1 Dec 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 23, 126745.

    Research output: Contribution to journalArticlepeer-review

  31. The first example of the stereoselective synthesis and crystal structure of a spirobicycloquinazolinone based on (-)-fenchone and anthranilamide

    Chernyshov, V. V., Gatilov, Y. V., Yarovaya, O. I., Koskin, I. P., Yarovoy, S. S., Brylev, K. A. & Salakhutdinov, N. F., 1 Dec 2019, In: Acta Crystallographica Section C: Structural Chemistry. 75, p. 1675-1680 6 p.

    Research output: Contribution to journalArticlepeer-review

  32. Synthesis of Camphecene and Cytisine Conjugates Using Click Chemistry Methodology and Study of Their Antiviral Activity

    Artyushin, O. I., Moiseeva, A. A., Zarubaev, V. V., Slita, A. V., Galochkina, A. V., Muryleva, A. A., Borisevich, S. S., Yarovaya, O. I., Salakhutdinov, N. F. & Brel, V. K., 29 Oct 2019, In: Chemistry and Biodiversity. 16, 11, e1900340.

    Research output: Contribution to journalArticlepeer-review

  33. Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells

    Kovaleva, K., Oleshko, O., Mamontova, E., Yarovaya, O., Zakharova, O., Zakharenko, A., Kononova, A., Dyrkheeva, N., Cheresiz, S., Pokrovsky, A., Lavrik, O. & Salakhutdinov, N., 27 Sept 2019, In: Journal of Natural Products. 82, 9, p. 2443-2450 8 p.

    Research output: Contribution to journalArticlepeer-review

  34. Synthesis of (1S)-(+)-camphor-10-sulfonic acid derivatives and investigations in vitro and in silico of their antiviral activity as the inhibitors of fi lovirus infections

    Sokolova, A. S., Baranova, D. V., Yarovaya, O. I., Baev, D. S., Polezhaeva, O. A., Zybkina, A. V., Shcherbakov, D. N., Tolstikova, T. G. & Salakhutdinov, N. F., 1 May 2019, In: Russian Chemical Bulletin. 68, 5, p. 1041-1046 6 p.

    Research output: Contribution to journalArticlepeer-review

  35. 2018
  36. Synthesis of d-(+)-camphor-based: N -acylhydrazones and their antiviral activity

    Kovaleva, K. S., Zubkov, F. I., Bormotov, N. I., Novikov, R. A., Dorovatovskii, P. V., Khrustalev, V. N., Gatilov, Y. V., Zarubaev, V. V., Yarovaya, O. I., Shishkina, L. N. & Salakhutdinov, N. F., 1 Dec 2018, In: MedChemComm. 9, 12, p. 2072-2082 11 p.

    Research output: Contribution to journalArticlepeer-review

  37. Selection of influenza virus resistant to the novel camphor-based antiviral camphecene results in loss of pathogenicity

    Zarubaev, V. V., Pushkina, E. A., Borisevich, S. S., Galochkina, A. V., Garshinina, A. V., Shtro, A. A., Egorova, A. A., Sokolova, A. S., Khursan, S. L., Yarovaya, O. I. & Salakhutdinov, N. F., 1 Nov 2018, In: Virology. 524, p. 69-77 9 p.

    Research output: Contribution to journalArticlepeer-review

  38. Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors

    Sokolova, A. S., Yarovaya, O. I., Bormotov, N. I., Shishkina, L. N. & Salakhutdinov, N. F., 1 Oct 2018, In: MedChemComm. 9, 10, p. 1746-1753 8 p.

    Research output: Contribution to journalArticlepeer-review

  39. Discovery of a New Class of Inhibitors of Vaccinia Virus Based on (−)-Borneol from Abies sibirica and (+)-Camphor

    Sokolova, A. S., Yarovaya, O. I., Bormotov, N. I., Shishkina, L. N. & Salakhutdinov, N. F., 1 Sept 2018, In: Chemistry and Biodiversity. 15, 9, 9 p., e1800153.

    Research output: Contribution to journalArticlepeer-review

  40. 3-N-ЗАМЕЩЕННЫЕ БОРНИЛПРОПИОНАТЫ, ИСПОЛЬЗУЕМЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ ВИРУСА МАРБУРГ

    Яровая, О. И., Соколова, А. С., Кононова, А. А., Чересиз, С. В., Никитина, Р. А., Чепурнов, А. А., Зайковская, А. В., Пьянков, О. В., Покровский, А. Г., Максютов, Р. А. & Салахутдинов, Н. Ф., 3 Apr 2018, IPC No. A61K31/4453, A61K31/452, A61P31/12, C07D211/14, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2649406, Priority date 21 Sept 2017, Priority No. 2017133088

    Research output: PatentPatent for invention

  41. Antiulcerogenic activity of borneol derivatives

    Borisova, M. S., Yarovaya, O. I., Semenova, M. D., Tolstikova, T. G. & Salakhutdinov, N. F., 1 Mar 2018, In: Russian Chemical Bulletin. 67, 3, p. 558-561 4 p.

    Research output: Contribution to journalArticlepeer-review

  42. Development and Validation of a Method for Determination of a New Effective Inhibitor of Influenza Virus H1N1 in Blood Plasma

    Sokolova, A. S., Yarovaya, O. I., Nefedov, A. A. & Salakhutdinov, N. F., Mar 2018, In: Pharmaceutical Chemistry Journal. 51, 12, p. 1102-1105 4 p.

    Research output: Contribution to journalArticlepeer-review

  43. 2017
  44. N-Heterocyclic borneol derivatives as inhibitors of Marburg virus glycoprotein-mediated VSIV pseudotype entry

    Kononova, A. A., Sokolova, A. S., Cheresiz, S. V., Yarovaya, O. I., Nikitina, R. A., Chepurnov, A. A., Pokrovsky, A. G. & Salakhutdinov, N. F., 1 Dec 2017, In: MedChemComm. 8, 12, p. 2233-2237 5 p.

    Research output: Contribution to journalArticlepeer-review

  45. Synthesis of camphecene derivatives using click chemistry methodology and study of their antiviral activity

    Artyushin, O. I., Sharova, E. V., Vinogradova, N. M., Genkina, G. K., Moiseeva, A. A., Klemenkova, Z. S., Orshanskaya, I. R., Shtro, A. A., Kadyrova, R. A., Zarubaev, V. V., Yarovaya, O. I., Salakhutdinov, N. F. & Brel, V. K., 15 May 2017, In: Bioorganic and Medicinal Chemistry Letters. 27, 10, p. 2181-2184 4 p.

    Research output: Contribution to journalArticlepeer-review

  46. One-pot synthesis of 1,5,3-oxathiazepanes via the three-component condensation of primary amines, formaldehyde and 2-mercaptoethanol

    Kovaleva, K. S., Yarovaya, O. I., Fadeev, D. S. & Salakhutdinov, N. F., 10 May 2017, In: Tetrahedron Letters. 58, 19, p. 1868-1870 3 p.

    Research output: Contribution to journalArticlepeer-review

  47. Synthesis and in vitro study of novel borneol derivatives as potent inhibitors of the influenza A virus

    Sokolova, A. S., Yarovaya, O. I., Semenova, M. D., Shtro, A. A., Orshanskaya, I. R., Zarubaev, V. V. & Salakhutdinov, N. F., 1 May 2017, In: MedChemComm. 8, 5, p. 960-963 4 p.

    Research output: Contribution to journalArticlepeer-review

  48. Synthesis and biological activity of heterocyclic borneol derivatives

    Sokolova, A. S., Yarovaya, О. I., Shtro, A. A., Borisova, M. S., Morozova, E. A., Tolstikova, T. G., Zarubaev, V. V. & Salakhutdinov, N. F., 1 Mar 2017, In: Chemistry of Heterocyclic Compounds. 53, 3, p. 371-377 7 p.

    Research output: Contribution to journalArticlepeer-review

  49. Synthesis of new heterocyclic dehydroabietylamine derivatives and their biological activity

    Kovaleva, K. S., Yarovaya, O. I., Shernyukov, A. V., Zarubaev, V. V., Shtro, A. A., Orshanskaya, Y. R. & Salakhutdinov, N. F., 1 Mar 2017, In: Chemistry of Heterocyclic Compounds. 53, 3, p. 364-370 7 p.

    Research output: Contribution to journalArticlepeer-review

  50. Aliphatic and alicyclic camphor imines as effective inhibitors of influenza virus H1N1

    Sokolova, A. S., Yarovaya, О. I., Baev, D. S., Shernyukov, А. V., Shtro, A. A., Zarubaev, V. V. & Salakhutdinov, N. F., 15 Feb 2017, In: European Journal of Medicinal Chemistry. 127, p. 661-670 10 p.

    Research output: Contribution to journalArticlepeer-review

  51. Effect of New Antiviral Agent Camphecin on Behavior of Mice

    Babina, A. V., Lavrinenko, V. A., Yarovaya, O. I. & Salakhutdinov, N. F., 1 Jan 2017, In: Bulletin of Experimental Biology and Medicine. 162, 3, p. 346-348 3 p.

    Research output: Contribution to journalArticlepeer-review

  52. 2016
  53. Development and validation of ultrafast LC–MS/MS method for quantification of anti-influenza agent camphecene in whole rat blood using dried blood spots and its application to pharmacokinetic studies

    Rogachev, A. D., Yarovaya, O. I., Ankov, S. V., Khvostov, M. V., Tolstikova, T. G., Pokrovsky, A. G. & Salakhutdinov, N. F., 15 Nov 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1036-1037, p. 136-141 6 p.

    Research output: Contribution to journalArticlepeer-review

ID: 3449511