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  1. 2026

  2. Recent Advances in Searching for DNMT Inhibitors and Their Potential Application in Treating Human Diseases

    Bulygin, A. A., Davletgildeeva, A. T. & Kuznetsov, N. A., 19 May 2026, In: International Journal of Molecular Sciences. 27, 10, 31 p., 4560.

    Research output: Contribution to journal › Review article › peer-review

  3. Coordination of Nucleoside Triphosphates in the Active Site of the Human TdT during Template-Independent DNA Synthesis

    Senchurova, S. I., Tyugashev, T. E. & Kuznetsov, N. A., 10 Feb 2026, In: Biochemistry (Moscow). 91, 1, p. 102-118 17 p.

    Research output: Contribution to journal › Article › peer-review

  4. The Role of Active Site Hydrophobic Interactions in Facilitating Catalysis in Human Terminal Deoxynucleotidyl Transferase

    Senchurova, S. I., Tyugashev, T. E. & Kuznetsov, N. A., 2026, In: International Journal of Molecular Sciences. 27, 1, 20 p., 178.

    Research output: Contribution to journal › Article › peer-review

  5. 2025

  6. Predictive Analysis and Validation of Critical Missense SNPs of the ABH2 Gene Using Structural Bioinformatics

    Davletgildeeva, A. T., Tyugashev, T. E., Sagalakova, V. V., Zhao, M. & Kuznetsov, N. A., 29 Nov 2025, In: International Journal of Molecular Sciences. 26, 23, 16 p., 11593.

    Research output: Contribution to journal › Article › peer-review

  7. Interplay Between DNA Polymerase, RNA Polymerase, and RNase H1 During Head-On Transcription-Replication Conflict

    Timofeyeva, N. A., Tsoi, E. I., Novopashina, D. S., Kuznetsov, N. A. & Kuznetsova, A. A., 27 Nov 2025, In: International Journal of Molecular Sciences. 26, 23, 22 p., 11515.

    Research output: Contribution to journal › Article › peer-review

  8. Biochemical Characterization of R-Loop Degradation by Chloroplast-Localized RNase H1 from Arabidopsis thaliana

    Gavrilova, A. A., Kuznetsova, A. A., Novopashina, D. S., Zheng, C., Sun, Q. & Kuznetsov, N. A., 17 Nov 2025, In: International Journal of Molecular Sciences. 26, 22, 13 p., 11125.

    Research output: Contribution to journal › Article › peer-review

  9. Engineering a Thermostable Reverse Transcriptase for RT-PCR Through Rational Design of Pyrococcus furiosus DNA Polymerase

    Kuznetsova, A. A., Grishina, I. A., Mikushina, E. S. & Kuznetsov, N. A., 24 Oct 2025, In: Biomolecules. 15, 11, 17 p., 1507.

    Research output: Contribution to journal › Article › peer-review

  10. Prospects for the structure‒function evolution of SARS-CoV-2 main protease inhibitors

    Bulygin, A. A. & Kuznetsov, N. A., 15 Sept 2025, In: Journal of Computer-Aided Molecular Design. 39, 1, 13 p., 78.

    Research output: Contribution to journal › Review article › peer-review

  11. Participants in Transcription–Replication Conflict and Their Role in Formation and Resolution of R-Loops

    Davletgildeeva, A. T. & Kuznetsov, N. A., 19 Jul 2025, In: International Journal of Molecular Sciences. 26, 14, 34 p., 6951.

    Research output: Contribution to journal › Review article › peer-review

  12. Role of Individual Amino Acid Residues Directly Involved in Damage Recognition in Active Demethylation by ABH2 Dioxygenase

    Davletgildeeva, A. T., Tyugashev, T. E., Zhao, M., Ishchenko, A. A., Saparbaev, M. & Kuznetsov, N. A., 18 Jul 2025, In: International Journal of Molecular Sciences. 26, 14, 23 p., 6912.

    Research output: Contribution to journal › Article › peer-review

  13. Molecular dynamic analysis of the functional role of amino acid residues V99, F124 and S125 of human DNA dioxygenase ABH2

    Zhao, M., Tyugashev, T. E., Davletgildeeva, A. T. & Kuznetsov, N. A., 2025, In: Vavilovskii Zhurnal Genetiki i Selektsii. 29, 7, p. 1062-1072 11 p., 14.

    Research output: Contribution to journal › Article › peer-review

  14. 2024

  15. Characterization and PCR Application of Family B DNA Polymerases from Thermococcus stetteri

    Kuznetsova, A. A., Soloveva, M. A., Mikushina, E. S., Gavrilova, A. A., Bakman, A. S. & Kuznetsov, N. A., 25 Nov 2024, In: Life. 14, 12, 1544.

    Research output: Contribution to journal › Article › peer-review

  16. Kinetic Features of Degradation of R-Loops by RNase H1 from Escherichia coli

    Kuznetsova, A. A., Kosarev, I. A., Timofeyeva, N. A., Novopashina, D. S. & Kuznetsov, N. A., 15 Nov 2024, In: International Journal of Molecular Sciences. 25, 22, 12263.

    Research output: Contribution to journal › Article › peer-review

  17. The Trajectory of Damaged-Base Eversion into the Active Site of Apurinic/Apyrimidinic Endonuclease APE1 Regulates This Enzyme’s Substrate Specificity

    Bulygin, A. A. & Kuznetsov, N. A., 15 Nov 2024, In: International Journal of Molecular Sciences. 25, 22, 12287.

    Research output: Contribution to journal › Article › peer-review

  18. Role of R-Loop Structure in Efficacy of RNA Elongation Synthesis by RNA Polymerase from Escherichia coli

    Timofeyeva, N. A., Tsoi, E. I., Novopashina, D. S., Kuznetsova, A. A. & Kuznetsov, N. A., 14 Nov 2024, In: International Journal of Molecular Sciences. 25, 22, 12190.

    Research output: Contribution to journal › Article › peer-review

  19. Bioremediation of Polycyclic Aromatic Hydrocarbons by Means of Bacteria and Bacterial Enzymes

    Davletgildeeva, A. T. & Kuznetsov, N. A., Sept 2024, In: Microorganisms. 12, 9, 1814.

    Research output: Contribution to journal › Article › peer-review

  20. Dealkylation of Macromolecules by Eukaryotic α-Ketoglutarate-Dependent Dioxygenases from the AlkB-like Family

    Davletgildeeva, A. T. & Kuznetsov, N. A., Sept 2024, In: Current issues in molecular biology. 46, 9, p. 10462-10491 30 p.

    Research output: Contribution to journal › Review article › peer-review

  21. The Role of DNMT Methyltransferases and TET Dioxygenases in the Maintenance of the DNA Methylation Level

    Davletgildeeva, A. T. & Kuznetsov, N. A., Sept 2024, In: Biomolecules. 14, 9, 1117.

    Research output: Contribution to journal › Article › peer-review

  22. An Insight into the Mechanism of DNA Cleavage by DNA Endonuclease from the Hyperthermophilic Archaeon Pyrococcus furiosus

    Davletgildeeva, A. T., Kuznetsova, A. A., Ishchenko, A. A., Saparbaev, M. & Kuznetsov, N. A., Aug 2024, In: International Journal of Molecular Sciences. 25, 16, 8897.

    Research output: Contribution to journal › Article › peer-review

  23. Computational Modeling Study of the Molecular Basis of dNTP Selectivity in Human Terminal Deoxynucleotidyltransferase

    Ukladov, E. O., Tyugashev, T. E. & Kuznetsov, N. A., Aug 2024, In: Biomolecules. 14, 8, 961.

    Research output: Contribution to journal › Article › peer-review

  24. SNP-Associated Substitutions of Amino Acid Residues in the dNTP Selection Subdomain Decrease Polβ Polymerase Activity

    Kladova, O. A., Tyugashev, T. E., Miroshnikov, A. A., Novopashina, D. S., Kuznetsov, N. A. & Kuznetsova, A. A., 2 May 2024, In: Biomolecules. 14, 5, 19 p., 547.

    Research output: Contribution to journal › Article › peer-review

  25. The Impact of SNP-Induced Amino Acid Substitutions L19P and G66R in the dRP-Lyase Domain of Human DNA Polymerase β on Enzyme Activities

    Kladova, O. A., Tyugashev, T. E., Yakimov, D. V., Mikushina, E. S., Novopashina, D. S., Kuznetsov, N. A. & Kuznetsova, A. A., 10 Apr 2024, In: International Journal of Molecular Sciences. 25, 8, 4182.

    Research output: Contribution to journal › Article › peer-review

  26. Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair

    Bakman, A. S., Boichenko, S. S., Kuznetsova, A. A., Ishchenko, A. A., Saparbaev, M. & Kuznetsov, N. A., Jan 2024, In: Biochimie. 216, p. 126-136 11 p.

    Research output: Contribution to journal › Article › peer-review

  27. Substrate Specificity Diversity of Human Terminal Deoxynucleotidyltransferase May Be a Naturally Programmed Feature Facilitating Its Biological Function

    Kuznetsova, A. A., Senchurova, S. I., Gavrilova, A. A., Tyugashev, T. E., Mikushina, E. S. & Kuznetsov, N. A., Jan 2024, In: International Journal of Molecular Sciences. 25, 2, 879.

    Research output: Contribution to journal › Article › peer-review

  28. Антибиотики

    Кузнецов, Н. А. & Булыгин, А. А., 2024, Новосибирск: ИПЦ НГУ. 78 p.

    Research output: Book/Report › Teaching materials › peer-review

  29. Механизмы узнавания 5-метилцитозина ферментами системы активного эпигенетического деметилирования

    Петрова, Д. В., Новопашина, Д. С., Кузнецова, А. А., Кузнецов, Н. А., Пермякова, Н. В., Грин, И. Р. & Жарков, Д. О., 2024, ФИЗИКО-ХИМИЧЕСКАЯ БИОЛОГИЯ: Материалы V всероссийской конференции, приуроченной к 40-летию ИХБФМ СО РАН. Новосибирск: ООО "Офсет ТМ", p. 25

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research

  30. 2023

  31. Historical Aspects of Restriction Endonucleases as Intelligent Scissors for Genetic Engineering

    Alekseeva, I. V. & Kuznetsov, N. A., Oct 2023, In: Fermentation. 9, 10, 874.

    Research output: Contribution to journal › Article › peer-review

  32. Direct Enzyme Engineering of B Family DNA Polymerases for Biotechnological Approaches

    Kuznetsova, A. A. & Kuznetsov, N. A., 30 Sept 2023, In: Bioengineering (Basel, Switzerland). 10, 10, 1150.

    Research output: Contribution to journal › Review article › peer-review

  33. Conformational Dynamics of Biopolymers in the Course of Their Interaction: Multifaceted Approaches to the Analysis by the Stopped-Flow Technique with Fluorescence Detection

    Kuznetsov, N. A., Sept 2023, In: Photonics. 10, 9, 1033.

    Research output: Contribution to journal › Article › peer-review

  34. Inner Amino Acid Contacts Are Key Factors of Multistage Structural Rearrangements of DNA and Affect Substrate Specificity of Apurinic/Apyrimidinic Endonuclease APE1

    Bulygin, A. A., Syryamina, V. N., Kuznetsova, A. A., Novopashina, D. S., Dzuba, S. A. & Kuznetsov, N. A., 14 Jul 2023, In: International Journal of Molecular Sciences. 24, 14, 11474.

    Research output: Contribution to journal › Article › peer-review

  35. Individual Contributions of Amido Acid Residues Tyr122, Ile168, and Asp173 to the Activity and Substrate Specificity of Human DNA Dioxygenase ABH2

    Davletgildeeva, A. T., Tyugashev, T. E., Zhao, M., Kuznetsov, N. A., Ishchenko, A. A., Saparbaev, M. & Kuznetsova, A. A., 13 Jul 2023, In: Cells. 12, 14, 1839.

    Research output: Contribution to journal › Article › peer-review

  36. Cloning, Expression, and Characterization of Family A DNA Polymerase from Massilia aurea

    Kuznetsova, A. A., Bedritskikh, K. S., Bulygin, A. A. & Kuznetsov, N. A., Jul 2023, In: Fermentation. 9, 7, 650.

    Research output: Contribution to journal › Article › peer-review

  37. The Impact of Human DNA Glycosylases on the Activity of DNA Polymerase β toward Various Base Excision Repair Intermediates

    Bakman, A. S., Boichenko, S. S., Kuznetsova, A. A., Ishchenko, A. A., Saparbaev, M. & Kuznetsov, N. A., 31 May 2023, In: International Journal of Molecular Sciences. 24, 11, 9594.

    Research output: Contribution to journal › Article › peer-review

  38. The Activity of Natural Polymorphic Variants of Human DNA Polymerase β Having an Amino Acid Substitution in the Transferase Domain

    Kladova, O. A., Tyugashev, T. E., Mikushina, E. S., Kuznetsov, N. A., Novopashina, D. S. & Kuznetsova, A. A., 2 May 2023, In: Cells. 12, 9, 1300.

    Research output: Contribution to journal › Article › peer-review

  39. Comparative Analysis of Family A DNA-Polymerases as a Searching Tool for Enzymes with New Properties

    Bulygin, A. A., Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., Apr 2023, In: Molecular Biology. 57, 2, p. 182-192 11 p.

    Research output: Contribution to journal › Article › peer-review

  40. DNA Probes for Analysis of the Activity of Key Enzymes of the Base Excision DNA Repair Pathway in Human Cells

    Alekseeva, I. V., Kuznetsova, A. A., Kladova, O. A., Shender, V. O., Schneider, P. V., Fedorova, O. S. & Kuznetsov, N. A., Apr 2023, In: Molecular Biology. 57, 2, p. 299-311 13 p.

    Research output: Contribution to journal › Article › peer-review

  41. Human Polβ Natural Polymorphic Variants G118V and R149I Affects Substate Binding and Catalysis

    Kladova, O. A., Tyugashev, T. E., Mikushina, E. S., Soloviev, N. O., Kuznetsov, N. A., Novopashina, D. S. & Kuznetsova, A. A., 20 Mar 2023, In: International Journal of Molecular Sciences. 24, 6, 5892.

    Research output: Contribution to journal › Article › peer-review

  42. Разработка и апробация ДНК-зондов для определения активности ключевых ферментов пути эксцизионной репарации оснований ДНК в клетках человека

    Alekseeva, I. V., Kuznetsova, A. A., Kladova, O. A., Шендер, В. О., Шнайдер, П. В., Fedorova, O. S. & Kuznetsov, N. A., 1 Mar 2023, In: Molekuliarnaia biologiia. 57, 2, p. 316-329 14 p., 15.

    Research output: Contribution to journal › Article › peer-review

  43. Fluorescently labeled human apurinic/apyrimidinic endonuclease APE1 reveals effects of DNA polymerase β on the APE1-DNA interaction

    Bakman, A. S., Kuznetsova, A. A., Yanshole, L. V., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., Mar 2023, In: DNA Repair. 123, 12 p., 103450.

    Research output: Contribution to journal › Article › peer-review

  44. Сравнительный анализ ДНК-полимераз семейства А как инструмент поиска ферментов с новыми свойствами

    Булыгин, А. А., Кузнецова, А. А., Федорова, О. С. & Кузнецов, Н. А., 2023, In: Molekulyarnaya Biologiya. 57, 2, p. 185-196 12 p., 5.

    Research output: Contribution to journal › Article › peer-review

  45. 2022

  46. Insight into the mechanism of DNA synthesis by human terminal deoxynucleotidyltransferase

    Kuznetsova, A. A., Tyugashev, T. E., Alekseeva, I. V., Timofeyeva, N. A., Fedorova, O. S. & Kuznetsov, N. A., 1 Dec 2022, In: Life science alliance. 5, 12, 16 p., e202201428.

    Research output: Contribution to journal › Article › peer-review

  47. Pre-steady-state kinetic and mutational insights into mechanisms of endo- and exonuclease DNA processing by mutant forms of human AP endonuclease

    Bakman, A. S., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., Dec 2022, In: Biochimica et Biophysica Acta - General Subjects. 1866, 12, 130198.

    Research output: Contribution to journal › Article › peer-review

  48. Kinetic Features of 3′–5′–Exonuclease Activity of Apurinic/Apyrimidinic Endonuclease Apn2 from Saccharomyces cerevisiae

    Kuznetsova, A. A., Gavrilova, A. A., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., Nov 2022, In: International Journal of Molecular Sciences. 23, 22, 14404.

    Research output: Contribution to journal › Article › peer-review

  49. The mechanism of damage recognition by apurinic/apyrimidinic endonuclease Nfo from Escherichia coli

    Senchurova, S. I., Syryamina, V. N., Kuznetsova, A. A., Novopashina, D. S., Ishchenko, A. A., Saparbaev, M., Dzuba, S. A., Fedorova, O. S. & Kuznetsov, N. A., Nov 2022, In: Biochimica et Biophysica Acta - General Subjects. 1866, 11, 130216.

    Research output: Contribution to journal › Article › peer-review

  50. The Kinetic Mechanism of 3′-5′ Exonucleolytic Activity of AP Endonuclease Nfo from E. coli

    Senchurova, S. I., Kuznetsova, A. A., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., Oct 2022, In: Cells. 11, 19, 2998.

    Research output: Contribution to journal › Article › peer-review

  51. Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy

    Kanazhevskaya, L. Y., Smyshliaev, D. A., Timofeyeva, N. A., Ishchenko, A. A., Saparbaev, M., Kuznetsov, N. A. & Fedorova, O. S., Aug 2022, In: Molecules. 27, 15, 4960.

    Research output: Contribution to journal › Article › peer-review

  52. Structural and Molecular Kinetic Features of Activities of DNA Polymerases

    Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 1 Jun 2022, In: International Journal of Molecular Sciences. 23, 12, 6373.

    Research output: Contribution to journal › Review article › peer-review

  53. Insights into Mechanisms of Damage Recognition and Catalysis by APE1-like Enzymes

    Bulygin, A. A., Fedorova, O. S. & Kuznetsov, N., 1 Apr 2022, In: International Journal of Molecular Sciences. 23, 8, 4361.

    Research output: Contribution to journal › Article › peer-review

  54. Comparative Analysis of Exo-and Endonuclease Activities of APE1-like Enzymes

    Davletgildeeva, A. T., Kuznetsova, A. A., Novopashina, D. S., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., 1 Mar 2022, In: International Journal of Molecular Sciences. 23, 5, 2869.

    Research output: Contribution to journal › Article › peer-review

  55. The Role of Natural Polymorphic Variants of DNA Polymerase β in DNA Repair

    Kladova, O. A., Fedorova, O. S. & Kuznetsov, N. A., 1 Feb 2022, In: International Journal of Molecular Sciences. 23, 4, 2390.

    Research output: Contribution to journal › Review article › peer-review

  56. 2021

  57. Pre-Steady-State Kinetics of the SARS-CoV-2 Main Protease as a Powerful Tool for Antiviral Drug Discovery

    Zakharova, M. Y., Kuznetsova, A. A., Uvarova, V. I., Fomina, A. D., Kozlovskaya, L. I., Kaliberda, E. N., Kurbatskaia, I. N., Smirnov, I. V., Bulygin, A. A., Knorre, V. D., Fedorova, O. S., Varnek, A., Osolodkin, D. I., Ishmukhametov, A. A., Egorov, A. M., Gabibov, A. G. & Kuznetsov, N. A., 6 Dec 2021, In: Frontiers in Pharmacology. 12, 773198.

    Research output: Contribution to journal › Article › peer-review

  58. Common kinetic mechanism of abasic site recognition by structurally different apurinic/apyrimidinic endonucleases

    Kuznetsova, A. A., Senchurova, S. I., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., 2 Aug 2021, In: International Journal of Molecular Sciences. 22, 16, 8874.

    Research output: Contribution to journal › Article › peer-review

  59. Mechanism of target nucleotide recognition and cleavage in the model non-canonical DNA and RNA structures by human AP-endonuclease APE1

    Davletgildeeva, A., Kuznetsova, A., Fedorova, O. & Kuznetsov, N., Jul 2021, In: FEBS Open Bio. 11, p. 246-246 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  60. Roles of active-site amino acid residues in RNA cleavage by human AP endonuclease APE1

    Kuznetsova, A., Gavrilova, A., Fedorova, O. & Kuznetsov, N., Jul 2021, In: FEBS Open Bio. 11, p. 246-246 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  61. Мутационный и кинетический анализ эндорибонуклеазной активности АРЕ1

    Kuznetsova, A. A., Gavrilova, A. A., Novopashina, D. S., Fedorova, O. S. & Kuznetsov, N. A., 20 Apr 2021, In: Molekuliarnaia biologiia. 55, 2, p. 243-257 15 p., 6.

    Research output: Contribution to journal › Article › peer-review

  62. The Enigma of Substrate Recognition and Catalytic Efficiency of APE1-Like Enzymes

    Davletgildeeva, A. T., Ishchenko, A. A., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., 26 Mar 2021, In: Frontiers in Cell and Developmental Biology. 9, p. 617161 617161.

    Research output: Contribution to journal › Article › peer-review

  63. Сравнительный анализ активности полиморфных вариантов урацил-ДНК-гликолиаз человека человека SMUG1 и MBD4

    Alekseeva, I. V., Bakman, A. S., Iakovlev, D. A., Kuznetsov, N. A. & Fedorova, O. S., 1 Mar 2021, In: Molekuliarnaia biologiia. 55, 2, p. 277-288 12 p., 9.

    Research output: Contribution to journal › Article › peer-review

  64. Comparative Analysis of the Activity of the Polymorphic Variants of Human Uracil-DNA-Glycosylases SMUG1 and MBD4

    Alekseeva, I., Bakman, A. S., Iakovlev, D. A., Kuznetsov, N. A. & Fedorova, O. S., Mar 2021, In: Molecular Biology. 55, 2, p. 241-251 11 p.

    Research output: Contribution to journal › Article › peer-review

  65. Mutational and Kinetic Analysis of APE1 Endoribonuclease Activity

    Kuznetsova, A. A., Gavrilova, A. A., Novopashina, D. S., Fedorova, O. S. & Kuznetsov, N. A., Mar 2021, In: Molecular Biology. 55, 2, p. 211-224 14 p., 5.

    Research output: Contribution to journal › Article › peer-review

  66. 2020

  67. Human Tyrosyl-DNA Phosphodiesterase 1 Possesses Transphosphooligonucleotidation Activity With Primary Alcohols

    Dyrkheeva, N., Anarbaev, R., Lebedeva, N., Kuprushkin, M., Kuznetsova, A., Kuznetsov, N., Rechkunova, N. & Lavrik, O., 23 Dec 2020, In: Frontiers in Cell and Developmental Biology. 8, 12 p., 604732.

    Research output: Contribution to journal › Article › peer-review

  68. The role of active-site amino acid residues in the cleavage of DNA and RNA substrates by human apurinic/apyrimidinic endonuclease APE1

    Alekseeva, I. V., Kuznetsova, A. A., Bakman, A. S., Fedorova, O. S. & Kuznetsov, N. A., 1 Dec 2020, In: Biochimica et Biophysica Acta - General Subjects. 1864, 12, 13 p., 129718.

    Research output: Contribution to journal › Article › peer-review

  69. Lesion Recognition and Cleavage of Damage-Containing Quadruplexes and Bulged Structures by DNA Glycosylases

    Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 30 Nov 2020, In: Frontiers in Cell and Developmental Biology. 8, 16 p., 595687.

    Research output: Contribution to journal › Article › peer-review

  70. Activity of Human Apurinic/Apyrimidinic Endonuclease APE1 Toward Damaged DNA and Native RNA With Non-canonical Structures

    Davletgildeeva, A. T., Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 30 Oct 2020, In: Frontiers in Cell and Developmental Biology. 8, 14 p., 590848.

    Research output: Contribution to journal › Article › peer-review

  71. Modulation of the apurinic/apyrimidinic endonuclease activity of human APE1 and of its natural polymorphic variants by base excision repair proteins

    Kladova, O. A., Alekseeva, I. V., Saparbaev, M., Fedorova, O. S. & Kuznetsov, N. A., 1 Oct 2020, In: International Journal of Molecular Sciences. 21, 19, p. 1-15 15 p., 7147.

    Research output: Contribution to journal › Article › peer-review

  72. The Role of Active-Site Plasticity in Damaged-Nucleotide Recognition by Human Apurinic/Apyrimidinic Endonuclease APE1

    Bulygin, A. A., Kuznetsova, A. A., Vorobjev, Y. N., Fedorova, O. S. & Kuznetsov, N. A., 1 Sept 2020, In: Molecules. 25, 17, 13 p., 3940.

    Research output: Contribution to journal › Article › peer-review

  73. Role of Arg243 and His239 Residues in the Recognition of Damaged Nucleotides by Human Uracil-DNA Glycosylase SMUG1

    Iakovlev, D. A., Alekseeva, I. V., Kuznetsov, N. A. & Fedorova, O. S., 1 May 2020, In: Biochemistry (Moscow). 85, 5, p. 594-603 10 p.

    Research output: Contribution to journal › Article › peer-review

  74. An Assay for the Activity of Base Excision Repair Enzymes in Cellular Extracts Using Fluorescent DNA Probes

    Kladova, O. A., Iakovlev, D. A., Groisman, R., Ishchenko, A. A., Saparbaev, M. K., Fedorova, O. S. & Kuznetsov, N. A., 1 Apr 2020, In: Biochemistry (Moscow). 85, 4, p. 480-489 10 p.

    Research output: Contribution to journal › Article › peer-review

  75. Chapter 11: Alternative DNA Repair Pathways to Handle Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs: Alternative DNA Repair Pathways to Handle Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs

    Федорова, О. С. & Кузнецов, Н. А., 2020, DNA Damage, DNA Repair and Disease: Volume 1. Dizdaroglu, M. & Lloyd, R. S. (eds.). London: Royal Society of Chemistry, Vol. 1. p. 249-278 30 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  76. Определение сравнительной активности ключевых ферментов эксцизионной репарации оснований в клеточных экстрактах

    Кладова, О. А., Яковлев, Д. А., Groisman, R., Ishchenko, A. A., Saparbaev, M. K., Федорова, О. С. & Кузнецов, Н. А., 2020, In: Биохимия. 85, 4, p. 556-566 11 p., 8.

    Research output: Contribution to journal › Article › peer-review

  77. Роль аминокислотных остатков Arg243 и His239 в процессе узнавания поврежденного нуклеотида урацил-ДНК-гликозилазой человека SMUG1

    Яковлев, Д. А., Алексеева, И. В., Кузнецов, Н. А. & Федорова, О. С., 2020, In: Биохимия. 85, 5, p. 695-705 11 p., 8.

    Research output: Contribution to journal › Article › peer-review

  78. 2019

  79. Role of Ionizing Amino Acid Residues in the Process of DNA Binding by Human AP Endonuclease 1 and in Its Catalysis

    Alekseeva, I. V., Bakman, A. S., Vorobjev, Y. N., Fedorova, O. S. & Kuznetsov, N. A., 14 Nov 2019, In: Journal of Physical Chemistry B. 123, 45, p. 9546-9556 11 p.

    Research output: Contribution to journal › Article › peer-review

  80. Comparative Analysis of Nucleotide Fluorescent Analogs for Registration of DNA Conformational Changes Induced by Interaction with Formamidopyrimidine-DNA Glycosylase Fpg

    Kuznetsova, A. A., Kladova, O. A., Barthes, N. P. F., Michel, B. Y., Burger, A., Fedorova, O. S. & Kuznetsov, N. A., 1 Nov 2019, In: Russian Journal of Bioorganic Chemistry. 45, 6, p. 591-598 8 p.

    Research output: Contribution to journal › Article › peer-review

  81. New Fluorescent Analogs of Nucleotides Based on 3-Hydroxychromone for Recording Conformational Changes of DNA

    Kladova, O. A., Kuznetsova, A. A., Barthes, N. P. F., Michel, B. Y., Burger, A., Fedorova, O. S. & Kuznetsov, N. A., 1 Nov 2019, In: Russian Journal of Bioorganic Chemistry. 45, 6, p. 599-607 9 p.

    Research output: Contribution to journal › Article › peer-review

  82. The role of active-site residues Phe98, HiS239, and Arg243 in DNA binding and in the catalysis of human uracil–DNA glycosylase SMUG1

    Iakovlev, D. A., Alekseeva, I. V., Vorobjev, Y. N., Kuznetsov, N. A. & Fedorova, O. S., 28 Aug 2019, In: Molecules. 24, 17, 12 p., 3133.

    Research output: Contribution to journal › Article › peer-review

  83. The impact of single-nucleotide polymorphisms of human apurinic/apyrimidinic endonuclease 1 on specific DNA binding and catalysis

    Alekseeva, I. V., Davletgildeeva, A. T., Arkova, O. V., Kuznetsov, N. A. & Fedorova, O. S., 1 Aug 2019, In: Biochimie. 163, p. 73-83 11 p.

    Research output: Contribution to journal › Article › peer-review

  84. Roles of Active-Site Amino Acid Residues in Specific Recognition of DNA Lesions by Human 8-Oxoguanine-DNA Glycosylase (OGG1)

    Tyugashev, T. E., Vorobjev, Y. N., Kuznetsova, A. A., Lukina, M. V., Kuznetsov, N. A. & Fedorova, O. S., 13 Jun 2019, In: Journal of Physical Chemistry B. 123, 23, p. 4878-4887 10 p.

    Research output: Contribution to journal › Article › peer-review

  85. Conformational Dynamics of Damage Processing by Human DNA Glycosylase NEIL1

    Kladova, O. A., Grin, I. R., Fedorova, O. S., Kuznetsov, N. A. & Zharkov, D. O., 15 Mar 2019, In: Journal of Molecular Biology. 431, 6, p. 1098-1112 15 p.

    Research output: Contribution to journal › Article › peer-review

  86. Thermodynamics of the DNA repair process by endonuclease VIII

    Kladova, O. A., Kuznetsov, N. A. & Fedorova, O. S., 1 Jan 2019, In: Acta Naturae. 11, 1, p. 29-37 9 p.

    Research output: Contribution to journal › Article › peer-review

  87. 2018

  88. Substrate specificity of human apurinic/apyrimidinic endonuclease APE1 in the nucleotide incision repair pathway

    Kuznetsova, A. A., Matveeva, A. G., Milov, A. D., Vorobjev, Y. N., Dzuba, S. A., Fedorova, O. S. & Kuznetsov, N. A., 30 Nov 2018, In: Nucleic Acids Research. 46, 21, p. 11454-11465 12 p.

    Research output: Contribution to journal › Article › peer-review

  89. Kinetic features of 30-50 exonuclease activity of human AP-endonuclease ape1

    Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 21 Aug 2018, In: Molecules. 23, 9, 14 p., 2101.

    Research output: Contribution to journal › Article › peer-review

  90. Effect of pH on DNA binding and catalysis of human apurinic/apyrimidinic endonuclease 1

    Alekseeva, I., Bakman, A., Vorobjev, Y., Fedorova, O. & Kuznetsov, N., Jul 2018, In: FEBS Open Bio. 8, p. 405-405 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  91. Evolution of inhibitor-resistant variants of HIV protease analyzed by pre-steady state kinetic analysis

    Zakharova, M., Kuznetsova, A., Kaliberda, E., Dronina, M., Kolesnikov, A., Kozyr, A., Smirnov, I., Rumsh, L., Fedorova, O., Knorre, D., Gabibov, A. & Kuznetsov, N., Jul 2018, In: FEBS Open Bio. 8, p. 290-291 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  92. New details of specific site recognition by human single-strand selective monofunctional uracil-DNA glycosylase SMUG1

    Iakovlev, D. A., Misovets, I. V., Alekseeva, I. A., Vorobjev, Y. N., Kuznetsov, N. A. & Fedorova, O. S., Jul 2018, In: FEBS Open Bio. 8, p. 446-447 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  93. Stopped-flow kinetic study of DNA demethylation by Fe(II)/2-oxoglutarate-dependent dioxygenase AlkB

    Kanazhevskaya, L., Alekseeva, I., Kuznetsov, N. & Fedorova, O., Jul 2018, In: FEBS Open Bio. 8, p. 415-415 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  94. Thermodynamic and kinetic analysis of specific lesion recognition by wild-type endonuclease III and its catalytic mutants

    Kladova, O., Kuznetsov, N. & Fedorova, O., Jul 2018, In: FEBS Open Bio. 8, p. 388-388 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  95. 2017

  96. Pre-steady-state kinetic analysis of damage recognition by human single-strand selective monofunctional uracil-DNA glycosylase SMUG1

    Kuznetsova, A. A., Iakovlev, D. A., Misovets, I. V., Ishchenko, A. A., Saparbaev, M. K., Kuznetsov, N. A. & Fedorova, O. S., 21 Nov 2017, In: Molecular BioSystems. 13, 12, p. 2638-2649 12 p.

    Research output: Contribution to journal › Article › peer-review

  97. Evolution of inhibitor-resistant natural mutant forms of HIV-1 protease probed by pre-steady state kinetic analysis

    Zakharova, M. Y., Kuznetsova, A. A., Kaliberda, E. N., Dronina, M. A., Kolesnikov, A. V., Kozyr, A. V., Smirnov, I. V., Rumsh, L. D., Fedorova, O. S., Knorre, D. G., Gabibov, A. G. & Kuznetsov, N. A., 1 Nov 2017, In: Biochimie. 142, p. 125-134 10 p.

    Research output: Contribution to journal › Article › peer-review

  98. Conformational dynamics of human dioxygenase ABH2 in the course of action on methylated DNA

    Iakovlev, D. A., Timofeyeva, N. A., Kuznetsov, N. A. & Fedorova, O. S., Sept 2017, In: FEBS Journal. 284, p. 109-110 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  99. Effect of downstream enzymes of base excision DNA repair pathway on the action of human DNA glycosylase MBD4

    Kladova, O., Iakovlev, D., Kuznetsov, N. & Fedorova, O., Sept 2017, In: FEBS Journal. 284, p. 112-112 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  100. Pre-steady state kinetics of DNA binding and abasic site hydrolysis by tyrosyl-DNA phosphodiesterase 1

    Kuznetsov, N. A., Lebedeva, N. A., Kuznetsova, A. A., Rechkunova, N. I., Dyrkheeva, N. S., Kupryushkin, M. S., Stetsenko, D. A., Pyshnyi, D. V., Fedorova, O. S. & Lavrik, O. I., 18 Aug 2017, In: Journal of Biomolecular Structure and Dynamics. 35, 11, p. 2314-2327 14 p.

    Research output: Contribution to journal › Article › peer-review

  101. Mutational and kinetic analysis of lesion recognition by Escherichia coli endonuclease VIII

    Kladova, O. A., Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 13 May 2017, In: Genes. 8, 5, 13 p., 140.

    Research output: Contribution to journal › Article › peer-review

  102. The formation of catalytically competent enzyme–substrate complex is not a bottleneck in lesion excision by human alkyladenine DNA glycosylase

    Kuznetsov, N. A., Kiryutin, A. S., Kuznetsova, A. A., Panov, M. S., Barsukova, M. O., Yurkovskaya, A. V. & Fedorova, O. S., 4 Apr 2017, In: Journal of Biomolecular Structure and Dynamics. 35, 5, p. 950-967 18 p.

    Research output: Contribution to journal › Article › peer-review

  103. Interaction features of adenine DNA glycosylase MutY from E. coli with DNA substrates

    Tyugashev, T. E., Kuznetsova, A. A., Kuznetsov, N. A. & Fedorova, O. S., 1 Jan 2017, In: Russian Journal of Bioorganic Chemistry. 43, 1, p. 13-22 10 p.

    Research output: Contribution to journal › Article › peer-review

  104. The kinetic analysis of recognition of the damaged nucleotides by mutant forms of the 8-oxoguanine DNA glycosylase hOGG1

    Lukina, M. V., Kuznetsova, A. A., Kuznetsov, N. A. & Fedorova, O. S., 1 Jan 2017, In: Russian Journal of Bioorganic Chemistry. 43, 1, p. 1-12 12 p.

    Research output: Contribution to journal › Article › peer-review

  105. Search for Modified DNA Sites with the Human Methyl-CpG-Binding Enzyme MBD4

    Yakovlev, D. A., Kuznetsova, A. A., Fedorova, O. S. & Kuznetsov, N. A., 2017, In: Acta Naturae. 9, 1, p. 26-37 12 p.

    Research output: Contribution to journal › Article › peer-review

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