1. 2019
  2. Increasing bioavailability of very poorly water-soluble compounds. A case study of an anti-tumor drug, soloxolon methyl

    Ogienko, A. G., Markov, A. V., Sen'kova, A. V., Logashenko, E. B., Salomatina, O. V., Myz, S. A., Ogienko, A. A., Nefedov, A. A., Losev, E. A., Drebushchak, T. N., Salakhutdinov, N. F., Boldyrev, V. V., Vlasov, V. V., Zenkova, M. A. & Boldyreva, E. V., 1 Feb 2019, In: Journal of Drug Delivery Science and Technology. 49, p. 35-42 8 p.

    Research output: Contribution to journalArticlepeer-review

  3. Inhibitory Effect of New Semisynthetic Usnic Acid Derivatives on Human Tyrosyl-DNA Phosphodiesterase 1

    Dyrkheeva, N., Luzina, O., Filimonov, A., Zakharova, O., Ilina, E., Zakharenko, A., Kuprushkin, M., Nilov, D., Gushchina, I., Švedas, V., Salakhutdinov, N. & Lavrik, O., 1 Jan 2019, In: Planta Medica. 85, 2, p. 103-111 9 p.

    Research output: Contribution to journalArticlepeer-review

  4. Neuroregeneration in Parkinson's Disease: From Proteins to Small Molecules

    Sidorova, Y. A., Volcho, K. P. & Salakhutdinov, N. F., 1 Jan 2019, In: Current Neuropharmacology. 17, 3, p. 268-287 20 p.

    Research output: Contribution to journalReview articlepeer-review

  5. Novel inhibitors of DNA repair enzyme TDP1 combining monoterpenoid and adamantane fragments

    Mozhaitsev, E. S., Zakharenko, A. L., Suslov, E. V., Korchagina, D. V., Zakharova, O. D., Vasil’eva, I. A., Chepanova, A. A., Black, E., Patel, J., Chand, R., Reynisson, J., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2019, In: Anti-Cancer Agents in Medicinal Chemistry. 19, 4, p. 463-472 10 p.

    Research output: Contribution to journalArticlepeer-review

  6. Novel tyrosyl-DNA phosphodiesterase 1 inhibitors enhance the therapeutic impact of topoteсan on in vivo tumor models

    Zakharenko, A. L., Luzina, O. A., Sokolov, D. N., Kaledin, V. I., Nikolin, V. P., Popova, N. A., Patel, J., Zakharova, O. D., Chepanova, A. A., Zafar, A., Reynisson, J., Leung, E., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2019, In: European Journal of Medicinal Chemistry. 161, p. 581-593 13 p.

    Research output: Contribution to journalArticlepeer-review

  7. The development of tyrosyl-DNA phosphodyesterase 1 (TDP1) inhibitors based on the amines combining aromatic/heteroaromatic and monoterpenoid moieties

    Mozhaitsev, E., Suslov, E., Demidova, Y., Korchagina, D., Volcho, K., Zakharenko, A., Vasil’eva, I., Kupryushkin, M., Chepanova, A., Ayine-Tora, D. M., Reynisson, J., Salakhutdinov, N. & Lavrik, O., 1 Jan 2019, In: Letters in Drug Design and Discovery. 16, 5, p. 597-605 9 p.

    Research output: Contribution to journalArticlepeer-review

  8. 2018
  9. Molecular and Supramolecular Structure of 8-(Trifluoromethyl)Benzo[f][1,2,3,4,5] Pentathiepin-6-Amine – A Representative of Condensed Arene Pentathiepines

    Rybalova, T. V., Rogachev, A. D., Khomenko, T. M., Volcho, K. P. & Salakhutdinov, N. F., 1 Dec 2018, In: Journal of Structural Chemistry. 59, 7, p. 1753-1758 6 p.

    Research output: Contribution to journalArticlepeer-review

  10. N,N'-(АЛКАНДИИЛ)БИС[ЛАБДА-7(9),13,14-ТРИЕН-4-КАРБОКСАМИДЫ], ОБЛАДАЮЩИЕ ПРОТИВООПУХОЛЕВОЙ АКТИВНОСТЬЮ

    Харитонов, Ю. В., Шульц, Э. Э., Сорокина, И. В., Сазонова, Л. В., Толстикова, Т. Г., Покровский, А. Г. & Покровский, М. А., 17 May 2018, IPC No. C07D407/12, A61K31/341, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2654201, Priority date 4 May 2017, Priority No. 2017116024

    Research output: PatentPatent for invention

  11. N-[3-ОКСОЛУП-20(29)-ЕН-28-ОИЛ]-2,2,6,6-ТЕТРАМЕТИЛПИПЕРИДИН-4-ИЛАМИН, ОБЛАДАЮЩИЙ ЦИТОТОКСИЧЕСКОЙ АКТИВНОСТЬЮ В ОТНОШЕНИИ ОПУХОЛЕВЫХ КЛЕТОК ЧЕЛОВЕКА

    Покровский, А. Г., Покровский, М. А., Чересиз, С. В., Шульц, Э. Э., Волкова, А. Н. & Петренко, Н. И., 23 Jan 2018, IPC No. C07J63/00, A61K31/58, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2641900, Priority date 27 Feb 2017, Priority No. 2017106550

    Research output: PatentPatent for invention

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