Fundamental Medicine Laboratory - Research output

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1-Адамантил-3-(((1R,4aS,10aR)-7-изопропил-1,4а-диметил-1,2,3,4,4а,9,10,10а-октагидрофенантрен-1-ил)метил)мочевина, проявляющая ингибирующее действие в отношении фермента тирозил-ДНК-фосфодиэстеразы 1 человека и увеличивающая активность темозоломида в отношении клеток глиобластомы
Олешко, О. С., Ковалева, К. С., Яровая, О. И., Мамонтова, Е. М., Захаренко, А. Л., Захарова, О. Д., Чересиз, С. В., Покровский, А. Г., Лаврик, О. И. & Салахутдинов, Н. Ф., 14 Aug 2019, IPC No. C07C275/22, C07C275/24, A61K31/17, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2697409, Priority date 30 Apr 2019, Priority No. 2019113591
Research output: Patent › Patent for invention
6-(4′-Aryl-1′,2′,3′-triazolyl)-spirostan-3,5-diols and 6-(4′-Aryl-1′,2′,3′-triazolyl)-7-hydroxyspirosta-1,4-dien-3-ones: Synthesis and analysis of their cytotoxicity
Mironov, M. E., Oleshko, O. S., Pokrovskii, M. A., Rybalova, T. V., Pechurov, V. K., Pokrovskii, A. G., Cheresis, S. V., Mishinov, S. V., Stupak, V. V. & Shults, E. E., 1 Nov 2019, In: Steroids. 151, p. 108460 10 p., 108460.
Research output: Contribution to journal › Article › peer-review
6-ГИДРОКСИНАФТОХИНОНЫ ЛАБДАНОВОГО ТИПА, ОБЛАДАЮЩИЕ ЦИТОТОКСИЧЕСКОЙ АКТИВНОСТЬЮ ПО ОТНОШЕНИЮ К ОПУХОЛЕВЫМ КЛЕТКАМ ЧЕЛОВЕКА
Шульц, Э. Э., Миронов, М. Е., Покровский, М. А., Шерман, К. М., Покровский, А. Г. & Толстиков, Г. А., 20 Apr 2013, IPC No. C07D307/40, A61K31/341, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2479582, Priority date 19 Apr 2012, Priority No. 2012115828
Research output: Patent › Patent for invention
Antimetastatic Activity of Combined Topotecan and Tyrosyl-DNA Phosphodiesterase-1 Inhibitor on Modeled Lewis Lung Carcinoma
Koldysheva, E. V., Men’shchikova, A. P., Lushnikova, E. L., Popova, N. A., Kaledin, V. I., Nikolin, V. P., Zakharenko, A. L., Luzina, O. A., Salakhutdinov, N. F. & Lavrik, O. I., 15 Mar 2019, In: Bulletin of Experimental Biology and Medicine. 166, 5, p. 661-666 6 p.
Research output: Contribution to journal › Article › peer-review
Antimicrobial Activity of Substituted Benzopentathiepin-6-amines
Khomenko, T. M., Korchagina, D. V., Baev, D. S., Vassiliev, P. M., Volcho, K. P. & Salakhutdinov, N. F., 1 Aug 2019, In: Journal of Antibiotics. 72, 8, p. 590-599 10 p.
Research output: Contribution to journal › Article › peer-review
Biostability study, quantitation method and preliminary pharmacokinetics of a new antifilovirus agent based on borneol and 3-(piperidin-1-yl)propanoic acid
Rogachev, A. D., Putilova, V. P., Zaykovskaya, A. V., Yarovaya, O. I., Sokolova, A. S., Fomenko, V. V., Pyankov, O. V., Maksyutov, R. A., Pokrovsky, A. G. & Salakhutdinov, N. F., 30 May 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 199, 114062.
Research output: Contribution to journal › Article › peer-review
Clay nanotubes catalyzed solvent-free synthesis of octahydro-2H-chromenols with pharmaceutical potential from (-)-isopulegol and ketones
Sidorenko, A. Y., Kravtsova, A. V., Il'ina, I. V., Wärnå, J., Korchagina, D. V., Gatilov, Y. V., Volcho, K. P., Salakhutdinov, N. F., Murzin, D. Y. & Agabekov, V. E., 1 Dec 2019, In: Journal of Catalysis. 380, p. 145-152 8 p.
Research output: Contribution to journal › Article › peer-review
Comparative Study of Fusogenic Activity of H1 and H5 Subtypes Influenza Virus Hemagglutinins
Kononova, A. A., Cheresiz, S. V., Chechushkov, A. V., Razumova, Y. V. & Pokrovskii, A. G., 1 Nov 2017, In: Bulletin of Experimental Biology and Medicine. 164, 1, p. 85-89 5 p.
Research output: Contribution to journal › Article › peer-review
Comparison of dried matrix spots and fabric phase sorptive extraction methods for quantification of highly potent analgesic activity agent (2R,4aR,7R,8aR)-4,7-dimethyl-2-(thiophen-2-yl)octahydro-2H-chromen-4-ol in rat whole blood and plasma using LC–MS/MS
Lastovka, A. V., Rogachev, A. D., Il'ina, I. V., Kabir, A., Volcho, K. P., Fadeeva, V. P., Pokrovsky, A. G., Furton, K. G. & Salakhutdinov, N. F., 15 Nov 2019, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1132, 121813.
Research output: Contribution to journal › Article › peer-review
Correlation of metabolic profiles of plasma and cerebrospinal fluid of high-grade glioma patients
Rogachev, A. D., Alemasov, N. A., Ivanisenko, V. A., Ivanisenko, N. V., Gaisler, E. V., Oleshko, O. S., Cheresiz, S. V., Mishinov, S. V., Stupak, V. V. & Pokrovsky, A. G., Mar 2021, In: Metabolites. 11, 3, p. 1-14 14 p., 133.
Research output: Contribution to journal › Article › peer-review

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ID: 14174273