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  1. 2021

  2. Dehydroabietylamine-based thiazolidin-4-ones and 2-thioxoimidazolidin-4-ones as novel tyrosyl-DNA phosphodiesterase 1 inhibitors

    Kovaleva, K., Mamontova, E., Yarovaya, O., Zakharova, O., Zakharenko, A., Lavrik, O. & Salakhutdinov, N., Nov 2021, In: Molecular Diversity. 25, 4, p. 2389-2397 9 p.

    Research output: Contribution to journal › Article › peer-review

  3. Stability study of the antiviral agent camphecene in dried blood spots at different temperatures

    Okhina, A. A., Rogachev, A. D., Yarovaya, O. I., Pokrovsky, A. G. & Salakhutdinov, N. F., Oct 2021, In: Drug Testing and Analysis. 13, 10, p. 1797-1802 6 p.

    Research output: Contribution to journal › Letter › peer-review

  4. Biostability study, quantitation method and preliminary pharmacokinetics of a new antifilovirus agent based on borneol and 3-(piperidin-1-yl)propanoic acid

    Rogachev, A. D., Putilova, V. P., Zaykovskaya, A. V., Yarovaya, O. I., Sokolova, A. S., Fomenko, V. V., Pyankov, O. V., Maksyutov, R. A., Pokrovsky, A. G. & Salakhutdinov, N. F., 30 May 2021, In: Journal of Pharmaceutical and Biomedical Analysis. 199, 114062.

    Research output: Contribution to journal › Article › peer-review

  5. Design, synthesis, and molecular docking study of new tyrosyl-dna phosphodiesterase 1 (Tdp1) inhibitors combining resin acids and adamantane moieties

    Kovaleva, K., Yarovaya, O., Ponomarev, K., Cheresiz, S., Azimirad, A., Chernyshova, I., Zakharenko, A., Konev, V., Khlebnikova, T., Mozhaytsev, E., Suslov, E., Nilov, D., Švedas, V., Pokrovsky, A., Lavrik, O. & Salakhutdinov, N., 1 May 2021, In: Pharmaceuticals. 14, 5, 422.

    Research output: Contribution to journal › Article › peer-review

  6. Unexpected Ring Opening During the Imination of Camphor-Type Bicyclic Ketones

    Chernyshov, V. V., Yarovaya, O. I., Vatsadze, S. Z., Borisevich, S. S., Trukhan, S. N., Gatilov, Y. V., Peshkov, R. Y., Eltsov, I. V., Martyanov, O. N. & Salakhutdinov, N. F., 22 Jan 2021, In: European Journal of Organic Chemistry. 2021, 3, p. 452-463 12 p.

    Research output: Contribution to journal › Article › peer-review

  7. 2020

  8. Monoterpenoid-based inhibitors of filoviruses targeting the glycoprotein-mediated entry process

    Sokolova, A. S., Yarovaya, O. I., Zybkina, A. V., Mordvinova, E. D., Shcherbakova, N. S., Zaykovskaya, A. V., Baev, D. S., Tolstikova, T. G., Shcherbakov, D. N., Pyankov, O. V., Maksyutov, R. A. & Salakhutdinov, N. F., 1 Dec 2020, In: European Journal of Medicinal Chemistry. 207, 17 p., 112726.

    Research output: Contribution to journal › Article › peer-review

  9. New chemical agents based on adamantane-monoterpene conjugates against orthopoxvirus infections

    Suslov, E. V., Mozhaytsev, E. S., Korchagina, D. V., Bormotov, N. I., Yarovaya, O. I., Volcho, K. P., Serova, O. A., Agafonov, A. P., Maksyutov, R. A., Shishkina, L. N. & Salakhutdinov, N. F., Oct 2020, In: RSC Medicinal Chemistry. 11, 10, p. 1185-1195 11 p.

    Research output: Contribution to journal › Article › peer-review

  10. 1,1’-(Гексан-1,6-диил)бис(3-(((1R,4aS,10aR)-7-изопропил-1,4a-диметил-1,2,3,4,4a,9,10,10a-октагидрофенантрен-1-ил)метил)мочевина, проявляющая ингибирующее действие в отношении фермента тирозил-ДНК-фосфодиэстеразы 1 человека и увеличивающая активность темозоломида в отношении клеток глиобластомы

    Ковалева, К. С., Олешко, О. С., Яровая, О. И., Мамонтова, Е. М., Захаренко, А. Л., Захарова, О. Д., Чересиз, С. В., Покровский, А. Г., Лаврик, О. И. & Салахутдинов, Н. Ф., 26 Jun 2020, IPC No. C07C275/24, A61K31/17, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2724882, Priority date 28 Nov 2019, Priority No. 2019138671

    Research output: Patent › Patent for invention

  11. Synthesis of cyclic D-(+)-camphoric acid imides and study of their antiviral activity

    Chernyshov, V. V., Yarovaya, O. I., Peshkov, R. Y. & Salakhutdinov, N. F., 1 Jun 2020, In: Chemistry of Heterocyclic Compounds. 56, 6, p. 763-768 6 p.

    Research output: Contribution to journal › Article › peer-review

  12. Development and validation of an LC-MS/MS method for the quantitative analysis of the anti-influenza agent camphecene in rat plasma and its application to study the blood-to-plasma distribution of the agent

    Охина, А. А., Rogachev, A. D., Yarovaya, O. I., Khvostov, M. V., Tolstikova, T. G., Покровский, А. Г., Khazanov, V. A. & Salakhutdinov, N. F., 20 Feb 2020, In: Journal of Pharmaceutical and Biomedical Analysis. 180, 11 p., 113039.

    Research output: Contribution to journal › Article › peer-review

  13. Single-stage synthesis of heterocyclic alkaloid-like compounds from (+)-camphoric acid and their antiviral activity

    Chernyshov, V. V., Yarovaya, O. I., Fadeev, D. S., Gatilov, Y. V., Esaulkova, Y. L., Muryleva, A. S., Sinegubova, K. O., Zarubaev, V. V. & Salakhutdinov, N. F., 1 Feb 2020, In: Molecular Diversity. 24, 1, p. 61-67 7 p.

    Research output: Contribution to journal › Article › peer-review

  14. 2019

  15. Synthesis and structure-activity relationships of novel camphecene analogues as anti-influenza agents

    Yarovaya, O. I., Sokolova, A. S., Mainagashev, I. Y., Volobueva, A. S., Lantseva, K., Borisevich, S. S., Shtro, A. A., Zarubaev, V. V. & Salakhutdinov, N. F., 1 Dec 2019, In: Bioorganic and Medicinal Chemistry Letters. 29, 23, 126745.

    Research output: Contribution to journal › Article › peer-review

  16. The first example of the stereoselective synthesis and crystal structure of a spirobicycloquinazolinone based on (-)-fenchone and anthranilamide

    Chernyshov, V. V., Gatilov, Y. V., Yarovaya, O. I., Koskin, I. P., Yarovoy, S. S., Brylev, K. A. & Salakhutdinov, N. F., 1 Dec 2019, In: Acta Crystallographica Section C: Structural Chemistry. 75, p. 1675-1680 6 p.

    Research output: Contribution to journal › Article › peer-review

  17. Synthesis of Camphecene and Cytisine Conjugates Using Click Chemistry Methodology and Study of Their Antiviral Activity

    Artyushin, O. I., Moiseeva, A. A., Zarubaev, V. V., Slita, A. V., Galochkina, A. V., Muryleva, A. A., Borisevich, S. S., Yarovaya, O. I., Salakhutdinov, N. F. & Brel, V. K., 29 Oct 2019, In: Chemistry and Biodiversity. 16, 11, e1900340.

    Research output: Contribution to journal › Article › peer-review

  18. Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells

    Kovaleva, K., Oleshko, O., Mamontova, E., Yarovaya, O., Zakharova, O., Zakharenko, A., Kononova, A., Dyrkheeva, N., Cheresiz, S., Pokrovsky, A., Lavrik, O. & Salakhutdinov, N., 27 Sept 2019, In: Journal of Natural Products. 82, 9, p. 2443-2450 8 p.

    Research output: Contribution to journal › Article › peer-review

  19. 1-Адамантил-3-(((1R,4aS,10aR)-7-изопропил-1,4а-диметил-1,2,3,4,4а,9,10,10а-октагидрофенантрен-1-ил)метил)мочевина, проявляющая ингибирующее действие в отношении фермента тирозил-ДНК-фосфодиэстеразы 1 человека и увеличивающая активность темозоломида в отношении клеток глиобластомы

    Олешко, О. С., Ковалева, К. С., Яровая, О. И., Мамонтова, Е. М., Захаренко, А. Л., Захарова, О. Д., Чересиз, С. В., Покровский, А. Г., Лаврик, О. И. & Салахутдинов, Н. Ф., 14 Aug 2019, IPC No. C07C275/22, C07C275/24, A61K31/17, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2697409, Priority date 30 Apr 2019, Priority No. 2019113591

    Research output: Patent › Patent for invention

  20. Synthesis of (1S)-(+)-camphor-10-sulfonic acid derivatives and investigations in vitro and in silico of their antiviral activity as the inhibitors of fi lovirus infections

    Sokolova, A. S., Baranova, D. V., Yarovaya, O. I., Baev, D. S., Polezhaeva, O. A., Zybkina, A. V., Shcherbakov, D. N., Tolstikova, T. G. & Salakhutdinov, N. F., 1 May 2019, In: Russian Chemical Bulletin. 68, 5, p. 1041-1046 6 p.

    Research output: Contribution to journal › Article › peer-review

  21. 2018

  22. Synthesis of d-(+)-camphor-based: N -acylhydrazones and their antiviral activity

    Kovaleva, K. S., Zubkov, F. I., Bormotov, N. I., Novikov, R. A., Dorovatovskii, P. V., Khrustalev, V. N., Gatilov, Y. V., Zarubaev, V. V., Yarovaya, O. I., Shishkina, L. N. & Salakhutdinov, N. F., 1 Dec 2018, In: MedChemComm. 9, 12, p. 2072-2082 11 p.

    Research output: Contribution to journal › Article › peer-review

  23. Untargeted search and identification of metabolites of antiviral agent camphecene in rat urine by liquid chromatography and mass spectrometry and studying their distribution in organs following peroral administration of the compound

    Rogachev, A. D., Yarovaya, O. I., Fatianova, A. V., Lavrinenko, V. A., Amosov, E. V., Zarubaev, V. V., Pokrovsky, A. G. & Salakhutdinov, N. F., 30 Nov 2018, In: Journal of Pharmaceutical and Biomedical Analysis. 161, p. 383-392 10 p.

    Research output: Contribution to journal › Article › peer-review

  24. Selection of influenza virus resistant to the novel camphor-based antiviral camphecene results in loss of pathogenicity

    Zarubaev, V. V., Pushkina, E. A., Borisevich, S. S., Galochkina, A. V., Garshinina, A. V., Shtro, A. A., Egorova, A. A., Sokolova, A. S., Khursan, S. L., Yarovaya, O. I. & Salakhutdinov, N. F., 1 Nov 2018, In: Virology. 524, p. 69-77 9 p.

    Research output: Contribution to journal › Article › peer-review

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