A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins

Sharapov, S., Timoshchuk, A., Zaytseva, O., Maslov, D. E., Soplenkova, A., Elgaeva, E. E., Tiys, E. S., Mangino, M., Wittenbecher, C., Karssen, L., Timofeeva, M., Nostaeva, A., Vuckovic, F., Trbojević-Akmačić, I., Štambuk, T., Feoktistova, S., Potapova, N. A., Voroshilova, V., Williams, F., Primorac, D., & 11 othersVan zundert, J., Georges, M., Suhre, K., Allegri, M., Chaturvedi, N., Dunlop, M., Schulze, M. B., Spector, T., Tsepilov, Y. A., Lauc, G. & Aulchenko, Y. S., 1 Jul 2025, In: Nature Communications. 16, 1, 5525.

Research output: Contribution to journal › Article › peer-review

A genome-wide association study of the plasma N-glycome of 10,000 individuals significantly expands the list of associated loci

Шарапов, С. Ж., Timoshchuk, A. N., Зайцева, О. О., Maslov, D., Soplenkova, A., Елгаева, Е. Е., Vuckovic, F., Trbojević-Akmačić, I., Williams, F. M. K., Primorac, D., Zundert, J. V., Georges, M., Suhre, K., Allegri, M., Chaturvedi, N., Dunlop, M. G., Schulze, M. B., Spector, T. D., Цепилов, Я. А., Lauc, G., & 1 othersАульченко, Ю. С., 2024, In: European journal of human genetics. 32, S2, p. 1177-1178 2 p., EP17.012.

Research output: Contribution to journal › Conference article › peer-review

Mapping of the gene network that regulates glycan clock of ageing

Frkatović-Hodžić, A., Mijakovac, A., Miškec, K., Nostaeva, A., Sharapov, S. Z., Landini, A., Haller, T., Akker, E. V. D., Sharma, S., Cuadrat, R. R. C., Mangino, M., Li, Y., Keser, T., Rudman, N., Štambuk, T., Pučić-Baković, M., Trbojević-Akmačić, I., Gudelj, I., Štambuk, J., Pribić, T., & 20 othersRadovani, B., Tominac, P., Fischer, K., Beekman, M., Wuhrer, M., Gieger, C., Schulze, M. B., Wittenbecher, C., Polasek, O., Hayward, C., Wilson, J. F., Spector, T. D., Köttgen, A., Vučković, F., Aulchenko, Y. S., Vojta, A., Krištić, J., Klarić, L., Zoldoš, V. & Lauc, G., 26 Dec 2023, In: Aging. 15, 24, p. 14509-14552 44 p.

Research output: Contribution to journal › Article › peer-review

Genetic regulation of post-translational modification of two distinct proteins

Landini, A., Trbojević-Akmačić, I., Navarro, P., Tsepilov, Y. A., Sharapov, S. Z., Vučković, F., Polašek, O., Hayward, C., Petrović, T., Vilaj, M., Aulchenko, Y. S., Lauc, G., Wilson, J. F. & Klarić, L., Dec 2022, In: Nature Communications. 13, 1, 1 p., 1586.

Research output: Contribution to journal › Article › peer-review

A Novel Framework for Analysis of the Shared Genetic Background of Correlated Traits

Svishcheva, G. R., Tiys, E. S., Elgaeva, E. E., Feoktistova, S. G., Timmers, P. R. H. J., Sharapov, S. Z., Axenovich, T. I. & Tsepilov, Y. A., Oct 2022, In: Genes. 13, 10, 1694.

Research output: Contribution to journal › Article › peer-review

Investigation of cytotoxic and antioxidative activity of 1,2,3-triazolyl-modified furocoumarins and 2,3-dihydrofurocoumarins

Ivanov, A. A., Ukladov, E. A., Kremis, S. A., Sharapov, S. Z., Baiborodin, S. I., Lipeeva, A. V., Shults, E. E. & Golubeva, T. S., Sept 2022, In: Protoplasma. 259, 5, p. 1321-1330 10 p.

Research output: Contribution to journal › Article › peer-review

Investigation of the causal relationships between human IgG N-glycosylation and 12 common diseases associated with changes in the IgG N-glycome

Zaytseva, O. O., Sharapov, S. Z., Perola, M., Esko, T., Landini, A., Hayward, C., Wilson, J. F., Lauc, G., Aulchenko, Y. S., Klarić, L. & Tsepilov, Y. A., 15 May 2022, In: Human Molecular Genetics. 31, 10, p. 1545-1559 15 p.

Research output: Contribution to journal › Article › peer-review

Association Between Human Gut Microbiome and N-Glycan Composition of Total Plasma Proteome

Petrov, V. A., Sharapov, S. Z., Shagam, L., Nostaeva, A. V., Pezer, M., Li, D., Hanić, M., McGovern, D., Louis, E., Rahmouni, S., Lauc, G., Georges, M. & Aulchenko, Y. S., 29 Apr 2022, In: Frontiers in Microbiology. 13, 811922.

Research output: Contribution to journal › Article › peer-review

Genome-wide association study identifies RNF123 locus as associated with chronic widespread musculoskeletal pain

Rahman, M. S., Winsvold, B. S., Chavez Chavez, S. O., Børte, S., Tsepilov, Y. A., Sharapov, S. Z., Aulchenko, Y. S., Hagen, K., Fors, E. A., Hveem, K., Zwart, J. A., Van Meurs, J. B., Freidin, M. B. & Williams, F. M. K., 1 Sept 2021, In: Annals of the rheumatic diseases. 80, 9, p. 1227-1235 9 p.

Research output: Contribution to journal › Article › peer-review

Multivariate genome-wide analysis of immunoglobulin G N-glycosylation identifies new loci pleiotropic with immune function

Shadrina, A. S., Zlobin, A. S., Zaytseva, O. O., Klarić, L., Sharapov, S. Z., D Pakhomov, E., Perola, M., Esko, T., Hayward, C., Wilson, J. F., Lauc, G., Aulchenko, Y. S. & Tsepilov, Y. A., 1 Jul 2021, In: Human Molecular Genetics. 30, 13, p. 1259-1270 12 p.

Research output: Contribution to journal › Article › peer-review

Nontrivial Replication of Loci Detected by Multi-Trait Methods

Ning, Z., Tsepilov, Y. A., Sharapov, S. Z., Wang, Z., Grishenko, A. K., Feng, X., Shirali, M., Joshi, P. K., Wilson, J. F., Pawitan, Y., Haley, C. S., Aulchenko, Y. S. & Shen, X., 3 Feb 2021, In: Frontiers in Genetics. 12, 627989.

Research output: Contribution to journal › Article › peer-review

Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts

Sharapov, S. Z., Shadrina, A. S., Tsepilov, Y. A., Elgaeva, E. E., Tiys, E. S., Feoktistova, S. G., Zaytseva, O. O., Vuckovic, F., Cuadrat, R., Jäger, S., Wittenbecher, C., Karssen, L. C., Timofeeva, M., Tillin, T., Trbojević-Akmačić, I., Štambuk, T., Rudman, N., Krištić, J., Šimunović, J., Momčilović, A., & 21 othersVilaj, M., Jurić, J., Slana, A., Gudelj, I., Klarić, T., Puljak, L., Skelin, A., Kadić, A. J., Van Zundert, J., Chaturvedi, N., Campbell, H., Dunlop, M., Farrington, S. M., Doherty, M., Dagostino, C., Gieger, C., Allegri, M., Williams, F., Schulze, M. B., Lauc, G. & Aulchenko, Y. S., 1 Feb 2021, In: Glycobiology. 31, 2, p. 82-88 7 p.

Research output: Contribution to journal › Article › peer-review

A study of causal relationships between human IgG N-glycosylation traits and twelve associated diseases

Zaitseva, O. O., Sharapov, S. Z., Klaric, L., Lauc, G. & Tsepilov, Y. A., Dec 2020, In: Glycobiology. 30, 12, p. 1132-1132 1 p.

Research output: Contribution to journal › Meeting Abstract › peer-review

The GWAS-MAP platform for aggregation of results of genome-wide association studies and the GWAS-MAP|homo database of 70 billion genetic associations of human traits

Shashkova, T. I., Gorev, D. D., Pakhomov, E. D., Shadrina, A. S., Sharapov, S. Z., Tsepilov, Y. A., Karssen, L. C. & Aulchenko, Y. S., Dec 2020, In: Vavilovskii Zhurnal Genetiki i Selektsii. 24, 8, p. 876-884 9 p., 9.

Research output: Contribution to journal › Article › peer-review

Loci and Genes Involved in Chronic Musculoskeletal Pain Identified via Analysis of Genetically Orthogonal Pain Phenotypes

Tsepilov, Y., Freidin, M., Shadrina, A., Elgaeva, E., Sharapov, S., van Zunder, J., Karssen, L., Suri, P., Williams, F. & Aulchenko, Y., Jul 2020, In: Human Heredity. 84, 4-5, p. 226-226 1 p.

Research output: Contribution to journal › Meeting Abstract › peer-review

Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies

Shadrina, A. S., Shashkova, T. I., Torgasheva, A. A., Sharapov, S. Z., Klarić, L., Pakhomov, E. D., Alexeev, D. G., Wilson, J. F., Tsepilov, Y. A., Joshi, P. K. & Aulchenko, Y. S., 26 Jun 2020, In: Scientific Reports. 10, 1, 15 p., 10486.

Research output: Contribution to journal › Article › peer-review

Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions

Tsepilov, Y. A., Freidin, M. B., Shadrina, A. S., Sharapov, S. Z., Elgaeva, E. E., Zundert, J. V., Karssen, L., Suri, P., Williams, F. M. K. & Aulchenko, Y. S., 25 Jun 2020, In: Communications Biology. 3, 1, 13 p., 329.

Research output: Contribution to journal › Article › peer-review